The role of CT- and ET-complexes in a FAD-dependent reductase 1 Suppression of electron-transfer to dioxygen by charge-transfer and electron- transfer complexes in the FAD-dependent reductase component of toluene dioxygenase
نویسندگان
چکیده
Background: Toluene dioxygenase reductase converts the redox equivalents of NADH under oxic conditions. Results: Reduced reductase forms a stable complex with NAD that shows slower electron transfer to dioxygen. Conclusions: Charge-transfer complex formation regulates the reactivity of the reductase. Significance: Charge-transfer complexes between flavins and nicotinamides are abundant and likely to have diverse mechanistic functions.
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